FZD4 and brain neoplasm: GRASP55 and GRASP65 have been shown to control the transport of proteins such as CD8α - a dendritic cell marker with increased expression in pro-inflammatory niches of brain tumors (Pituch et al., 2018) - and Frizzled-4 (FZD4), both containing valine residues at the C-terminal during Golgi trafficking (D'Angelo et al., 2009).