NTS and neoplasm: High levels of TTK in the tumor tissues of lung cancer patients promote the growth of cancer cells by upregulation of neurotensin, enhance the expression of DPYSL3, and promote cell migration and epithelial mesenchymal transformation, thereby enhancing the metastasis potential and ultimately leading to tumor metastasis, which is positively correlated with adverse clinical outcomes of patients (Tsai et al. 2020).