LP17 has also been shown to be an effective treatment for sepsis secondary to Pseudomonas aeruginosa pneumonia in rats, resulting in with improved hemodynamic status, attenuated lactic acidosis and hypoxemia, reduced serum TNF-α, IL-1β, and IL-6, and improved 7-day survival of the septic rats (76). The gene discussed is TNF; the disease is Sepsis.