We further demonstrated that SA-hCD137L in a tetrameric form of human CD137L protein obviously enhanced the therapeutic effects of adoptive transfer of ex vivo expanded Vγ9Vδ2-T cell in Rag2-/-γc-/- mice and direct administration of PAM in humanized mice for the treatment of EBV-induced lymphoma with IL-10high TME. Here, GC is linked to lymphoma.