TNFRSF9 and neoplasm: To determine whether CD137 costimulation could rescue the impaired antitumor efficacy of Vγ9Vδ2-T cells in suppressive TME, the recombinant SA-hCD137L protein was added to the coculture of Vγ9Vδ2-T cells with EBV-LCL in IL-10high CM for mimicking the tumor milieu.