POMC and hemorrhagic disease: We cannot exclude, however, that this “vWF-disease”, albeit not presenting with any clinically relevant bleeding disorder, may have altered the STS effect on the GR expression: ACTH secreting bronchial carcinoid cells were shown to present with significant glucocorticoid receptor expression (38), and high glucocorticoid levels due to Cushing’s disease are associated with increased vWF-activity (39).