Of those, ST6 β-Galactoside α-2,6-Sialyltransferase 1 (ST6GAL1) and Core 1 β,3-Galactosyltransferase 1 (C1GALT1) seemed to be involved in the changes in the glycosylation pattern induced by the fungus on keratinocyte-derived sEVs, i.e. both enzymes are upregulated in AD and Ps and expressed in the majority of skin cell populations, including all subopulations of (proliferating, undifferentiated and differentiated) keratinocytes. Here, ST6GAL1 is linked to Alzheimer disease.