CD4 and systemic lupus erythematosus: Longevity and stemness function of TSCM can act as a double-edged sword as protective or pathogenic, as the evidence shows disrupting TSCM cell reservoirs in retroviral infections such as CD4+ TSCM or in autoimmune diseases such as aplastic anaemia, rheumatoid arthritis, type I diabetes and SLE, might be a target in diseases controlling strategy.