In addition to affecting DCs in the TME, Wnt3a and Wnt5a, albeit not directly shown in cancer, affect neutrophil maturation and recruitment, with Wnt5a being shown to act as a chemoattractant and induce CXCL8 and CCL2 from neutrophils, two chemokines recently implicated in OSCC progression and invasion (324–328). Here, WNT5A is linked to cancer.