The NAFLD liver fat score takes into consideration fasting serum insulin, AST, AST/ALT ratio, and the presence of MetS and/or type 2 diabetes, with a sensitivity of 84% and a specificity of 69% to predict NAFLD according to the results obtained in a study developed by Kotronen et al. [53,56,67,68]. The gene discussed is INS; the disease is type 2 diabetes mellitus.