The partial merge of ANXA1 with CD31, integrin-α8, synaptopodin, LTL, NE and CD68 was observed in renal specimens of AAV patients, which suggested that ANXA1 expressed in glomerular endothelial cells, mesangial cells, podocytes, proximal tubular epithelial cells, neutrophils and monocytes/macrophages (Figures 5A–D,F,G). This evidence concerns the gene SYNPO and anti-neutrophil cytoplasmic antibody-associated vasculitis.