To analyze the molecular mechanism of LINC00461 regulating DLBCL cell apoptosis, based on the principle of ceRNA, the corresponding miRNA was obtained using blast in the NCBI database, and then, the downstream target gene BNIP3 was obtained through online databases (https://targetscan.org, https://mirdb.org, https://microRNA.org). The gene discussed is BNIP3; the disease is diffuse large B-cell lymphoma.