In order to further analyze the relationship between LINC00461/miR-411-5p/BNIP3 at the clinical level, the expression of LINC00461, miR-411-5p, and BNIP3 mRNA in 65 cases of DLBCL was detected by RT-qPCR. The gene discussed is BNIP3; the disease is diffuse large B-cell lymphoma.