Our results showed that p-SLC16A1 and SLC16A1 were both downregulated in the model group, indicating that the significant metabolic disorders in proteins, cholesterol, fatty acids, and glucose in rabbits were induced by large dosages of snake venom, which not only induced the injury on neurons and cognitive function but also impacted the normal metabolic progression. The gene discussed is SLC16A1; the disease is metabolic disease.