NFKBIA and coronary artery disorder: In this study, we found that PPAR-α signaling pathway was significantly activated in the myocardial tissue of CHD rats and administration of JuA greatly inhibited the phosphorylation of p65 and IκBα in the myocardial tissue of CHD rats, suggesting that JuA could inhibit activation of PPAR-α signaling pathway, which was compatible with results in the study by Shu et al. [17].