It is a natural compound with antitumor activity, predominantly inhibiting cancer cell growth, and proliferation through weakening oncogenic growth signals, such as protein kinase B (AKT), mitogen-activated protein kinase (MAPK), HER-2, Wnt/-catenin, and phosphatidylinositol 3-kinase (PI3K) [46]. This evidence concerns the gene AKT1 and cancer.