Functional analysis of dysregulated genes in CRC samples showed that cell cycle-related processes “organelle fission,” “mitotic nuclear division,” “DNA replication,” and “regulation of mitotic cell cycle,” tumor-related pathways, such as “cytokine-cytokine receptor interaction,” and immune-related pathways, such as “Cell cycle,” “TNF signaling pathway,” and “p53 signaling pathway,” were significantly enriched, implying that these dysregulated pathways may be important mechanisms of CRC progression. This evidence concerns the gene TNF and colorectal carcinoma.