TP53 and neoplasm: Functional analysis of dysregulated genes in CRC samples showed that cell cycle-related processes “organelle fission,” “mitotic nuclear division,” “DNA replication,” and “regulation of mitotic cell cycle,” tumor-related pathways, such as “cytokine-cytokine receptor interaction,” and immune-related pathways, such as “Cell cycle,” “TNF signaling pathway,” and “p53 signaling pathway,” were significantly enriched, implying that these dysregulated pathways may be important mechanisms of CRC progression.