ABCA12 and familial pancreatic carcinoma: In the scratch healing experiment, the healing area of ABCA12 knockdown cells increased significantly 48 h later (Figure 4C), and the number of cells crossing the subtractal compartment in the Transwell experiment decreased significantly after ABCA12 knockdown, suggesting that the metastatic and invasion ability of pancreatic cancer cells was weakened after ABCA12 silencing (Figures 5A,B).