The time spent in central area (Figure 3E) and the ratio of total distance travelled in the central area (Figure 3F) were significantly increased in Fmr1 KO mice, suggesting that Fmr1 KO mice manifested reduced anxiety-like behavior compared with the WT mice, which was consistent with other reports (Yan et al., 2004; Zieba et al., 2019). Here, FMR1 is linked to Anxiety.