In addition, FCRLB also showed a significant positive correlation with M2-like macrophage genes (Figure 10C), as well as genes associated with epithelial-to-mesenchymal transition (EMT), which is a well-documented transdifferentiation program playing a critical role in cancer metastasis (Ievgenia and Cédric, 2019) and chemoresistance (Zheng et al., 2015) (Figure 10D). The gene discussed is FCRLB; the disease is cancer.