The GSEA revealed that FCRLB was enriched in substantial gene sets, including epithelial-to-mesenchymal transition (EMT) in colorectal cancer (NES = 1.345, FDR <0.05) (Figure 8B), PI3/AKT signaling pathway (NES = 1.323, FDR <0.05) (Figure 8C), cytokine and cytokine receptor interaction (NES = 1.323, FDR <0.05) (Figure 8D), interleukin-18 (IL-18) signaling pathway (NES = 1.363, FDR <0.05) (Figure 8E), extracellular matrix organization (NES = 1.650, FDR <0.05) (Figure 8F), and Galphaq signal (NES = 1.331, FDR <0.05) (Figure 8G). This evidence concerns the gene PI3 and colorectal cancer.