In addition, the content of activated dendritic cells (aDCs) was remarkably declined in OA patients, while the contents of B cells, check-point, cytolytic activity, HLA, inflammation-promoting, macrophages, mast cells, neutrophils, parainflammation, T cell co-inhibition, T cell co-stimulation, T helper cells, tumor-infiltrating lymphocytes (TIL), Type I IFN response, and Type II IFN response were obviously elevated (Figure 4C). The gene discussed is IFNA1; the disease is neoplasm.