EGFR and colorectal carcinoma: CAV1 can affect the occurrence and development of CRC through different mechanisms, including via activation of SLC2A3/GLUT3 transcription (Ha and Chi, 2012), suppressing phosphorylation of epidermal growth factor receptor (Yang et al., 2018), and stimulating HMGA1-mediated GLUT3 transcription (Ha et al., 2012).