ATP2A1 and colorectal cancer: Univariate analysis showed that high expression of ATP2A1 resulted in poor prognosis in patients with colorectal cancer [p < 0.01, hazard ratio (HR) = 2.032 (95%CI (1.251–3.302))] and TNM stage, lymphatic invasion, and tumor stage are also independent risk factors [p < 0.01, hazard ratio (HR > 1)] (Figure 2A).