BRCA1 and hypoparathyroidism-retardation-dysmorphism syndrome: The recognition of biallelic germline or somatic mutations in BRCA1/2 is, to date, one of the most clinically relevant and frequently used genetic biomarkers of homologous recombination repair deficiency (HRD) in the clinics (Dougherty et al., 2017; Hoppe et al., 2018).