GSEA results showed that the high-risk score is involved in cell cycle, splice some, DNA replication, mismatch repair, homologous recombination, proteasome, nucleoside precision repair, p53 signaling pathway, base precision repair, oocyte meiosis, regulation of actin cytoskeleton, pathways in cancer, and among other mechanisms (Figure S3 and Table 5). This evidence concerns the gene TP53 and cancer.