Moreover, AD and HL, as aging diseases, shared the similar mechanisms of neuroinflammation and oxidative stress, which precipitated P-tau deposition and MMP-3 expression, and both of them in turn promoted oxidative stress and neuroinflammation, producing plenty of free radicals and neuroinflammatory factors (Kim and Hwang, 2011). This evidence concerns the gene MAPT and Hodgkins lymphoma.