Changes in glutamate transport and recycling have been implicated in AD; most studies show a decreased expression of glutamate transporters or glutamine synthetase in the brains of AD patients (Masliah et al., 2000; Scott et al., 2011) and AD animal models (Minkeviciene et al., 2008; Kulijewicz-Nawrot et al., 2013). The gene discussed is GLUL; the disease is Alzheimer disease.