IL2RG and Wiskott-Aldrich syndrome: Similar to SCIDs, other types of PIDs that can be treated by allo-HSCT are in principle eligible for autologous HSCs gene therapy [67], [68], [70], [72], such as Wiskott-Aldrich syndrome (WAS), chronic granulomatous disease (CGD), recombination activating gene severe combined immunodeficiency (RAG1, RAG2) and so on.