MED23 and hyperthyroidism: For hyperthyroidism, we found a solitary significant association on chromosome B2 (P = 1.25 × 10−7 in LMM, P = 1.36 × 10−7 in FarmCPU), located in the gene Arginase 1 (ARG1) and 5.5 kb downstream of, although not in LD with, the gene Mediator Complex Subunit 23 (MED23) (Figure 3A).