The expanded region includes diseases nodes (purple hexagons) related to “Endocrine” diseases, namely: “Hypothyroidism,” “Goiter,” “Thyroid hormone resistance,” “Total iodide organization defect,” “Graves disease” and “Autoimmune thyroid disease.” Interestingly, the disease highlighted with a green circle represents a type of cancer called “Thyroid carcinoma.” In this case, the TSHR-gene bridges the diseases Hyperthyroidism (Endocrine) and “Thyroid carcinoma” (Cancer). Here, TSHR is linked to thyroid gland carcinoma.