CXCL8 and encephalitis: Another study analyzed the cerebrospinal fluid profiles during the 3–7 days of the course of disease in eight patients with SFTS with suspected acute encephalitis/encephalopathy and found that six patients were positive for SFTSV RNA in cerebrospinal fluid, and MCP-1 and IL-8 levels in cerebrospinal fluid were significantly higher than those in serum (Park et al., 2018) (see the section of “Host immune response–Cytokines–Acute phase–Correlation between cytokines and encephalitis” for details).