HP and dengue disease: For the clinical translation, the evaluation of gut barrier defects in patients with dengue and the strengthening gut integrity (probiotics, short-chain fatty acid, and/or zonulin alteration) (Seo et al., 2021; Hoilat et al., 2022), LPS absorption (Lipcsey et al., 2020), and BG removal (Ohata et al., 2003) might be the interesting adjuvant therapies that attenuate the disease mortality.