Several research today showed that mutations in the RAS family of genes especially the KRAS are linked to around a third of all malignancies; however, the incidence of the gene mutations varies greatly depending on the kind of cancer: often seen to be 40% in colorectal cancer, 15-20% in non-small-cell lung cancer, and 95% in pancreas carcinoma [44]. Here, KRAS is linked to familial pancreatic carcinoma.