Like the KRAS gene, BRAF is also part of the Ras family that targets the RAS/RAF/MEK/ERK pathway; together, they both account for 7-25% and 5-20% of all cancers as well as 30-45% and 8–10% of CRC for both KRAS and BRAF, respectively [8, 9]. Here, KRAS is linked to colorectal carcinoma.