Several poor prognostic factors, such as poor performance status, older age, number of metastatic organs, high serum lactate dehydrogenase (LDH) level, high serum CRP level, low serum albumin level, leukocytosis, high NLR, and visceral metastasis, were commonly mentioned in previous studies.30, 31, 32, 33, 34, 35, 36. Here, CRP is linked to Increased total leukocyte count.