RBM17 and acute myeloid leukemia: In addition, RBM17 knockdown in primary AML cells significantly impaired survival (Fig. 2c, Supplementary Fig. 2j–l) and reduced colony numbers (Fig. 2d–h, Supplementary Fig. 2m), indicating that RBM17 is required for supporting AML survival and progenitor colony-forming potential in vitro.