Therefore, we stained frontal cortex and hippocampus sections of human AD, tau-only Frontotemporal lobar degeneration (FTLD-tau), as well as neurologically healthy controls (CTR) lacking neuropathological signs of neurodegenerative diseases and AD, with LAMP5-specific antibodies (Fig. 2; Supplementary Table 2; Supplementary Fig. 4 and 5, online resource). Here, LAMP5 is linked to frontotemporal dementia.