The top five pathways according to p value were SPINK1 Pancreatic Cancer Pathway, EIF2 Signaling (p = 1.05E−7), Aryl Hydrocarbon Receptor Signaling (p = 1.05E−7), Clathrin-mediated Endocytosis Signaling (p = 2.3E−7), and Actin Cytoskeleton Signaling (p = 2.44E−7). This evidence concerns the gene SPINK1 and familial pancreatic carcinoma.