POLE and ovarian endometrioid carcinoma: Detection of POLE hotspot mutations (P286R and V411L) in 251 samples of different subtypes of ovarian cancer in China showed that the POLE S297F mutation is more common in ovarian endometrioid carcinoma than other types of mutations, supporting that the POLE S297F mutation may actively participate in the pathogenesis of ovarian endometrioid carcinoma [62].