It has been reported that the clusters of AuNPs, i.e., AuNCs, of ~ 88 nm size consisting of albumin-AuNPs (~ 4.5 nm) (AuNCs/BSA-AuNPs) showed significant hyperthermia effect in the HCT116 colon cancer mice model after laser irradiation (1.5 W/cm2, 10 min), suppressing tumor growth [115]. The gene discussed is ALB; the disease is neoplasm.