LGR5 and teratoma: Before applying RNAscope to FFPE human ovary pathologies, we tested its ability to detect LGR5 transcripts using ovarian mature teratoma samples and confirmed its specificity by demonstrating LGR5-positive cells in the bulb and outer root sheath of hair follicles, which is a well-known location for LGR5 cells (Supplementary Fig. 1).