Disease-free survival (DFS) data indicated high expression of TOP2A was related to poor DFS in cancers of ACC (p = 0.005), KICH (p = 0.042), KIRC (p < 0.001), KIRP (p < 0.001), LGG (p < 0.001), LIHC (p < 0.001), MESO (p = 0.012), PAAD (p = 0.001), PRAD (p < 0.001), SARC (p = 0.019), THCA (p = 0.003) and UVM (p = 0.004) (Fig. 2B). This evidence concerns the gene TOP2A and adrenal cortex carcinoma.