EVs from MDAMB231/NIS-stable donor cells increased 125I uptake of recipient Huh7, HepG2, and T47D cancer cells to 545.4 ± 47.2%, 1641.2 ± 114.7%, and 597.5 ± 11.0% of the control level, respectively (Fig. 4c). Here, SLC5A5 is linked to cancer.