In addition, FADS1 is also associated with metabolic diseases (obesity, metabolic syndrome) and cardiovascular diseases (arterial hypertension, coronary heart disease)48,49, In this study, FADS1 was up-regulated in Duolang sheep, which was consistent with previous study showing that FADS1 was highly expressed in subcutaneous adipose tissue of other species. The gene discussed is FADS1; the disease is coronary artery disorder.