In our study, we will find out whether IL-7 regulate autophagy via p53, AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR) and light chain 3 (LC3, also known as mammalian homolog of Atg8)8 in NSCLC cell line. This evidence concerns the gene TP53 and non-small cell lung carcinoma.