To examine whether this was affected by T cell Abca1/Abcg1 deficiency, we co-incubated wild-type bone marrow derived macrophages (BMDMs) with conditioned medium from αCD3/IL-2 stimulated Ldlr−/− or T-AbcdkoLdlr−/− CD8+ T cells prior to infection with E.coli bacteria. The gene discussed is CD8A; the disease is infection.