Broadly, thyroid disorders can result in PHTN in 2 ways, directly affecting the pulmonary vascular system and contributing to other medical conditions, which can ultimately lead to PHTN.[33] Scicchitano et al have proposed multi-mechanistic pathophysiology behind the development of PHTN in patients with HTH.[1] The direct effects of raised thyroid hormones cause a hyperdynamic pulmonary blood flow via an increased cardiac output. Here, TG is linked to thyroid gland disorder.