Because the increase in sCr value may be observed in the late stages of AKI, the urinary biomarkers such as neutrophil gelatinase-associated lipocalin and cystatin C have been studied for the early detection of cisplatin-induced nephrotoxicity.[13] During the review of the literature, it was found that there were limited data on whether the evaluation of urinary calprotectin might be useful for the early detection of acute cisplatin nephrotoxicity. This evidence concerns the gene LCN2 and acute kidney injury.