The summary sensitivity and specificity of Xpert MTB/RIF were 30% (95%CI: 21%–42%) and 99% (95%CI: 97%–100%) for diagnosing tuberculous pleurisy in Zhen-Yu Huo’s meta-analysis.[4] This method of combining a pleural lactate dehydrogenase (LDH) to adenosine deaminase (ADA) ratio and a pleural CEA level had a sensitivity of 62.0% and a specificity of 91.0%.[5] Similarly, sensitivity was not satisfactory. The gene discussed is ADA; the disease is pleural tuberculosis.