Furthermore, the expression level of tau in oligodendrocytes and astrocytes in DM1 needs further investigation as it was found to play a role in impairment of neuronal network and the spread of pathological tau in a number of neurodegenerative diseases like Alzheimer’s disease, progressive supranuclear palsy and Pick’s disease [52–54]. The gene discussed is MAPT; the disease is progressive supranuclear palsy.