LRRK2 and Parkinson disease: Cells were transfected with wildtype LRRK2, distinct point mutants described to increase PD risk (R1628P, S1647T, N2081D, G2385R), or the pathogenic Y1699C point mutant which served as a positive control (Ross et al., 2008; Lesage et al., 2009; Abdalla-Carvalho et al., 2010; Ross et al., 2011; Zheng et al., 2011; Fu et al., 2013; Hui et al., 2018).