RAB8A and Parkinson disease: We previously showed that pathogenic LRRK2 also causes deficits in the cohesion between centrosomes in a manner mediated by phospho-Rab8/10 and RILPL1, including in peripheral cells derived from LRRK2 PD patients (Madero-Pérez et al., 2018; Lara Ordóñez et al., 2019).