Others have also observed an inverse correlation in ID1 and ID2 expression in patients’ chronic myelogenous leukemia (CML) and blast crisis cells and in nonhematopoietic tissue, where loss of ID2 expression and overexpression of ID1 promote colon and breast cancer (11, 74–76). This evidence concerns the gene ID1 and chronic myelogenous leukemia, BCR-ABL1 positive.