NOTCH1 and diffuse large B-cell lymphoma: Our GSEA results revealed that the tumorigenicity of CXCR4 in DLBCL is related to the PI3K/AKT/mitogen-activated protein kinase (MAPK) pathways, mTOR, JNK-MAPK signal transducer and activator of transcription (STAT) pathways, Smad2/3/4, NOTCH1, and WNT signal pathways (Figure 2(d)) [19, 20].