However, rs2009112 [1.85 (1.11, 3.1) p 0.016], rs2796821 [1.72 (1.1.2.69) p 0.017] and rs2796822 [1.71 (1.07,2.71) p 0.022] in the TGF-β2 gene between patients with non-severe and severe asthma appear to stand out. This evidence concerns the gene TGFB2 and asthma.